Ventilation, RBCs and O2 transport; CO2 metabolism

Human Physiology and Anatomy 231

Summer Learning Plan

Overview

Ventilation is the process of moving gas into and out of the lungs. Gas exchange moves O2 and CO2 between the blood and the lungs, and red blood cells carry O2 to the tissues.

BEFORE CLASS

Read pp. 829-840-

Do the respiratory pathway quiz at http://msjensen.education.umn.edu/webanatomy/respiratory/res_gross_anat_1_s.html

Bring to Tuesday Class

Printout of the respiratory anatomy quiz

Tuesday Class – Heart Function

MAP the process of inspiration and expiration. http://www.getbodysmart.com/ap/respiratorysystem/zonesdivisions/tutorial.html

WRITE notes on the anatomy of alveoli, surfactant, and how gas is transferred from the air in the alveoli into the blood.

WRITE notes on the regulation of respiration through peripheral and central chemoreceptors.

USE hemoglobin saturation curves to predict transport of gases between body compartments. (Quant practice)

DETERMINE the effects of carbon dioxide on the binding of oxygen to hemoglobin. http://www.getbodysmart.com/ap/respiratorysystem/physiology/gases/phaffects/animation.html

At Home Learning Activities

ANSWER questions 9-11,13,19-22, and 26-27 on page 872.

Read pages 854-864

REVIEW the red blood cell life cycle at: http://faculty.alverno.edu/bowneps/epoiesis/epoiesisindex.htm

Explain why each of these persons has trouble supplying Oxygen to their cells.

1. Someone without surfactant

2. Someone whose phrenic nerve is cut

3. Someone who has inactive bone marrow due to chemotherapy

4. Someone who has an enlarged spleen

5. Someone who has disseminated intravascular clotting in the pulmonary arterioles

6. Someone who has fluid in the alveoli due to pneumonia

7. Someone who has a malformed epiglottis due to a birth defect

8. Someone who has a stab wound perforating the body wall between the 5th and 6th ribs

9. Someone who has had both kidneys removed

10. Someone who has reduced lung compliance

12. Someone who has reduced lung elasticity

Bring to Thursday Class

·	Your answers to the at-home questions

Thursday Class – Cardiac Cycle and Blood Flow

DISCUSS at-home questions

REVIEW carbon dioxide transport (http://faculty.alverno.edu/bowneps/co2metabolism/co2index.htm)

WRITE and DRAW notes on the function of central and peripheral chemoreceptors

DISCUSS the ways the body has of regulating blood pH

SOLVE this problem:

A man has long-standing COPD, and for many years his pCO2 has been abnormally high and his pH has been low. His respiration rate is normal. Why isn’t it elevated?

You are caring for this man in the clinic, and he complains all the time about being short of breath. One day he convinces you to turn up his O2 flow. When you come back, he is in a coma. Why?

ASSESSMENT ON BREATHING AND GAS TRANSPORT